Article Open Access

Bioinformatics in Sustainable Healthcare and Energy Efficiency

Saif Saad Ahmed, Sumaia Ali Alal, Mina Louay Badran, Samer Saeed Issa, Ghada S. Mohammed, M. Batumalay

Abstract


While originating in genomics, bioinformatics is emerging as a powerful tool for optimizing complex, energy-intensive systems. This paper investigates a novel application of bioinformatics across four critical sectors—healthcare, biofuel production, renewable energy, and the Internet of Things (IoT)—to enhance energy efficiency, operational reliability, and system adaptability. Using a mixed-methods approach that combines statistical modeling, algorithm development, and institutional case studies, this research quantifies the impact of bioinformatics-driven interventions on key performance and energy metrics. The results demonstrate significant and consistent improvements across all domains. In healthcare, integrating genomic analytics and adaptive controls led to energy savings of up to 12.8%. For biofuel production, bio-inspired enzymatic and microbial process optimization reduced energy intensity by as much as 18.1% per liter. In the renewable energy sector, bioinformatics-based modeling increased the net efficiency of a solar farm by 50%. Furthermore, IoT systems with embedded bioinformatics algorithms achieved up to 15.8% improvement in energy-aware operations, confirming the methodology's cross-disciplinary value. This study positions bioinformatics not merely as a scientific tool but as a core organizing principle for fostering sustainability in digitized infrastructures. While challenges such as computational overhead and ethical governance remain, this research provides compelling evidence that bioinformatics can serve as a catalyst for cross-industrial environmental innovation. Future work should focus on integration with high-performance computing and the development of socio-ethical frameworks to ensure scalable and responsible deployment for energy efficiency.


Keywords


Bioinformatics, Sustainable Healthcare, Energy Efficiency, Genomics, Computational Biology.

References


Olorunsogo, T., Balogun, O., Ayo-Farai, O., Ogundairo, O., Maduka, C., Okongwu, C., & Onwumere, C., Bioinformatics and personalized medicine in the U.S.: A comprehensive review: Scrutinizing the advancements in genomics and their potential to revolutionize healthcare delivery. World Journal of Advanced Research and Reviews, 2024. 21(01): p. 335–351.

Scarpa, F. and M. Casu Genomics and Bioinformatics in One Health: Transdisciplinary Approaches for Health Promotion and Disease Prevention. International Journal of Environmental Research and Public Health, 2024. 21, DOI: 10.3390/ijerph21101337.

Udayakumar, R., et al. Integrated Bio-Inspired Approach for Industrial Energy Management Systems. in 2023 International Conference for Technological Engineering and its Applications in Sustainable Development (ICTEASD). 2023.

Isaev, E., Kornilov, V., & Grigoriev, A., Data Center Efficiency Model: A New Approach and the Role of Artificial Intelligence. Mathematical Biology and Bioinformatics, 2023. 18(1).

Stecyk, A. and I. Miciu?a Harnessing the Power of Artificial Intelligence for Collaborative Energy Optimization Platforms. Energies, 2023. 16, DOI: 10.3390/en16135210.

Biswas, A., et al., Revolutionizing Biological Science: The Synergy of Genomics in Health, Bioinformatics, Agriculture, and Artificial Intelligence. OMICS: A Journal of Integrative Biology, 2023. 27(12): p. 550-569.

Dewi, A., & Adhi, C., Bioinformatics in Action: A Comprehensive Review of Bioinformatics Applications in Varied Disciplines. Indonesian Journal of Computer Science, 2024. 13(3).

M. S. Hasibuan, R. R. Isnanto, D. A. Dewi, J. Triloka, R. Z. A. Aziz, T. B. Kurniawan, A. Maizary, and A. Wibaselppa, “Integrating Convolutional Neural Networks into Mobile Health: A Study on Lung Disease Detection,” Journal of Applied Data Sciences, vol. 6, no. 3, pp. 1495–1503, 2025, doi: 10.47738/jads.v6i3.660.

D. Sugianto, R. Arindra Putawa, C. Izumi, and S. A. Ghaffar, “Uncovering the Efficiency of Phishing Detection: An In-depth Comparative Examination of Classification Algorithms,” International Journal for Applied Information Management, vol. 4, no. 1, pp. 22–29, 2024, doi: 10.47738/ijaim.v4i1.72.

S. F. Pratama and A. M. Wahid, “Fraudulent Transaction Detection in Online Systems Using Random Forest and Gradient Boosting,” Journal of Cyber Law, vol. 1, no. 1, pp. 88–115, 2025, doi: 10.63913/jcl.v1i1.5.

H. T. Sukmana and L. K. Oh, “Using K-Means Clustering to Enhance Digital Marketing with Flight Ticket Search Patterns,” Journal of Digital Market and Digital Currency, vol. 1, no. 3, pp. 286–304, 2024, doi: 10.47738/jdmdc.v1i3.22.

Nachammai, K.T., et al., Exploration of Bioinformatics on Microbial Fuel Cell Technology: Trends, Challenges, and Future Prospects. Journal of Chemistry, 2023. 2023(1): p. 6902054.

Kong, K.G.H., et al., Towards data-driven process integration for renewable energy planning. Current Opinion in Chemical Engineering, 2021. 31: p. 100665.

D. Sugianto and A. R. Hananto, “Geospatial Analysis of Virtual Property Prices Distributions and Clustering,” International Journal Research on Metaverse, vol. 1, no. 2, pp. 127–141, 2024, doi: 10.47738/ijrm.v1i2.10.

B. H. Hayadi and I. M. M. El Emary, “Enhancing Security and Efficiency in Decentralized Smart Applications through Blockchain Machine Learning Integration,” Journal of Current Research in Blockchain, vol. 1, no. 2, pp. 139–154, 2024, doi: 10.47738/jcrb.v1i2.16.

Sarmini, C. R. A. Widiawati, D. R. Febrianti, and D. Yuliana, “Volatility Analysis of Cryptocurrencies using Statistical Approach and GARCH Model a Case Study on Daily Percentage Change,” Journal of Applied Data Sciences, vol. 5, no. 3, pp. 838–848, 2024, doi: 10.47738/jads.v5i3.261.

Mostepaniuk, A., T. Akalin, and M.R. Parish Practices Pursuing the Sustainability of A Healthcare Organization: A Systematic Review. Sustainability, 2023. 15, DOI: 10.3390/su15032353.

Grealey, J., et al., The Carbon Footprint of Bioinformatics. Molecular Biology and Evolution, 2022. 39(3): p. msac034.

K. Y. Tippayawong, “Construction of Enterprise Logistics Decision Model Based on Supply Chain Management,” International Journal of Informatics and Information Systems, vol. 6, no. 4, pp. 181–188, 2023, doi: 10.47738/ijiis.v6i4.179.

N. Boyko, “Data Processing and Optimization in the Development of Machine Learning Systems: Detailed Requirements Analysis, Model Architecture, and Anti-Data Drift Strategies,” Journal of Applied Data Sciences, vol. 5, no. 3, pp. 1110–1122, 2024, doi: 10.47738/jads.v5i3.278.

Milicchio, F. and M. Prosperi. Experimental Survey on Power Dissipation of k-mer-Handling Data Structures for Mobile Bioinformatics. in 2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). 2021.

A. Febriani, R. Wahyuni, Mardeni, Y. Irawan, and R. Melyanti, “Improved Hybrid Machine and Deep Learning Model for Optimization of Smart Egg Incubator,” Journal of Applied Data Sciences, vol. 5, no. 3, pp. 1052–1563, 2024, doi: 10.47738/jads.v5i3.304.

M. L. Doan, “Predicting Online Course Popularity Using LightGBM: A Data Mining Approach on Udemy’s Educational Dataset,” Artificial Intelligence in Learning, vol. 1, no. 2, pp. 137–152, 2025, doi: 10.63913/ail.v1i2.11.

Chen, M., Y. Chen, and Q. Zhang A Review of Energy Consumption in the Acquisition of Bio-Feedstock for Microalgae Biofuel Production. Sustainability, 2021. 13, DOI: 10.3390/su13168873.

Raman, R., et al. Navigating the Nexus of Artificial Intelligence and Renewable Energy for the Advancement of Sustainable Development Goals. Sustainability, 2024. 16, DOI: 10.3390/su16219144.

Waltersmann, L., et al. Artificial Intelligence Applications for Increasing Resource Efficiency in Manufacturing Companies—A Comprehensive Review. Sustainability, 2021. 13, DOI: 10.3390/su13126689.

Kalyanakumar, P., et al. Harnessing Bio-Inspired Optimization and Swarm Intelligence for Energy-Aware TinyML in IoT. in 2024 International Conference on Inventive Computation Technologies (ICICT). 2024.

FatehiJananloo, M., H. Stopps, and J. McArthur, Exploring artificial intelligence methods for energy prediction in healthcare Facilities: An In-Depth extended systematic review. Energy and Buildings, 2024: p. 114598.

Djihene, A., B. Amal, and K. Ali. Enhance Energy Using Bio-Inspired Algorithms in Manet: An Overview. in 2024 2nd International Conference on Electrical Engineering and Automatic Control (ICEEAC). 2024.

Nwosu, N., Reducing operational costs in healthcare through advanced BI tools and data integration. World Journal of Advanced Research and Reviews, 2024. 22(03): p. 1144-1156.

W. Y. Leong, "Digital Technology for ASEAN Energy," 2023 International Conference on Circuit Power and Computing Technologies (ICCPCT), August 2023, pp. 1480-1486. DOI: 10.1109/ICCPCT58313.2023.10244806.




DOI: https://doi.org/10.52088/ijesty.v5i4.1760

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Copyright (c) 2025 Saif Saad Ahmed, Sumaia Ali Alal, Mina Louay Badran, Samer Saeed Issa, Ghada S. Mohammed, M. Batumalay

International Journal of Engineering, Science, and Information Technology (IJESTY) eISSN 2775-2674